Motif ID: HOX{A5,B5}.p2

Z-value: 1.231


Transcription factors associated with HOX{A5,B5}.p2:

Gene SymbolEntrez IDGene Name
HOXA5 3202 homeobox A5
HOXB5 3215 homeobox B5



Activity profile for motif HOX{A5,B5}.p2.

activity profile for motif HOX{A5,B5}.p2


Sorted Z-values histogram for motif HOX{A5,B5}.p2

Sorted Z-values for motif HOX{A5,B5}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOX{A5,B5}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_112010233 1.568 NM_001012993
C9orf152
chromosome 9 open reading frame 152
chr7_+_5289079 1.176 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr3_-_46481346 1.047 NM_002343
LTF
lactotransferrin
chr19_-_51168396 0.998 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr7_+_45899621 0.920


chr17_+_71109734 0.895 MYO15B
myosin XVB pseudogene
chrX_+_128700605 0.779 NM_003399
XPNPEP2
X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound
chr1_+_160618143 0.774 NM_001085375
C1orf226
chromosome 1 open reading frame 226
chr15_-_72804763 0.763 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr19_-_56537189 0.707 NM_001163922
VSIG10L
V-set and immunoglobulin domain containing 10 like
chr3_-_51968995 0.705 PCBP4
poly(rC) binding protein 4
chr1_+_144124547 0.693 NM_145277
NM_202004
NM_213652
NM_213653
HFE2



hemochromatosis type 2 (juvenile)



chr11_+_66152309 0.671


chr17_+_6620275 0.670 NM_153230
FBXO39
F-box protein 39
chr19_-_56919032 0.627 NM_001523
HAS1
hyaluronan synthase 1
chr10_-_7699192 0.577 ITIH5
inter-alpha (globulin) inhibitor H5
chr11_-_6633427 0.575 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr3_-_42892636 0.563 NM_004391
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr3_+_185300660 0.552 NM_182589
HTR3E
5-hydroxytryptamine (serotonin) receptor 3, family member E
chr4_+_109033868 0.512 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chrX_-_111212659 0.502 NM_012471
TRPC5
transient receptor potential cation channel, subfamily C, member 5
chr14_+_20568184 0.497 NM_173846
TPPP2
tubulin polymerization-promoting protein family member 2
chr10_+_104580420 0.496


chrX_+_7147471 0.492 NM_000351
STS
steroid sulfatase (microsomal), isozyme S
chr11_-_56905178 0.486 NM_006093
PRG3
proteoglycan 3
chr19_+_46207335 0.475 CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chr7_+_45894480 0.474 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chrX_-_104352005 0.468 NM_031274
TEX13A
testis expressed 13A
chr1_-_41259973 0.461 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr8_-_30826074 0.461 NM_031271
TEX15
testis expressed 15
chr22_+_23921072 0.458 KIAA1671
KIAA1671
chrX_+_48265107 0.458 NM_006579
EBP
emopamil binding protein (sterol isomerase)
chr19_-_51236113 0.458 NM_001002923
IGFL4
IGF-like family member 4
chr10_+_122206455 0.457 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chrX_+_51562894 0.454 NM_001005332
MAGED1
melanoma antigen family D, 1
chr11_+_36274300 0.450 NM_001160167
PRR5L
proline rich 5 like
chrX_+_54851500 0.448 NM_014599
MAGED2
melanoma antigen family D, 2
chr6_+_31662954 0.438 NM_001166538
NM_007161
NM_205840
LST1


leukocyte specific transcript 1


chr20_+_2972267 0.436 NM_001501
NM_178331
NM_178332
GNRH2


gonadotropin-releasing hormone 2


chr1_-_159459999 0.436 NM_001643
APOA2
apolipoprotein A-II
chr18_+_73090913 0.427 NM_001480
GALR1
galanin receptor 1
chr12_+_6751930 0.426 NM_002286
LAG3
lymphocyte-activation gene 3
chr11_-_59237893 0.422 NM_001005324
OR10V1
olfactory receptor, family 10, subfamily V, member 1
chr8_+_21972804 0.417 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr19_-_54958326 0.408 NM_021733
TSKS
testis-specific serine kinase substrate
chrX_+_144707022 0.391 NM_001144003
NM_001144004
NM_001144005
NM_032539
SLITRK2



SLIT and NTRK-like family, member 2



chr11_+_20027185 0.388 NAV2
neuron navigator 2
chr8_+_21972631 0.385 NM_001114138
NM_001978
EPB49

erythrocyte membrane protein band 4.9 (dematin)

chr16_-_1971180 0.383 NM_172167
NM_172168
NOXO1

NADPH oxidase organizer 1

chrX_-_139414890 0.381 NM_005634
SOX3
SRY (sex determining region Y)-box 3
chrX_-_130250880 0.363 IGSF1
immunoglobulin superfamily, member 1
chrX_-_8729377 0.363 NM_001171186
NM_174951
FAM9A

family with sequence similarity 9, member A

chrX_+_103297891 0.361 NM_207318
FAM199X
family with sequence similarity 199, X-linked
chrX_+_14457340 0.360 NM_001118885
NM_001118886
NM_001171942
NM_002063
GLRA2



glycine receptor, alpha 2



chrX_-_148394570 0.359 NM_000202
NM_001166550
NM_006123
IDS


iduronate 2-sulfatase


chrX_-_130251068 0.358 NM_001170961
NM_001170962
NM_001555
NM_205833
IGSF1



immunoglobulin superfamily, member 1



chr9_-_28709302 0.356 NM_152570
LINGO2
leucine rich repeat and Ig domain containing 2
chr13_+_57103944 0.353 PCDH17
protocadherin 17
chr8_-_143996257 0.352 NM_000498
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
chr20_+_42417502 0.351 HNF4A
hepatocyte nuclear factor 4, alpha
chr3_-_42892195 0.348 CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr19_-_47040347 0.348 NM_173506
LYPD4
LY6/PLAUR domain containing 4
chr4_+_152417774 0.347 NM_183375
PRSS48
protease, serine, 48
chrX_+_48253007 0.346 NM_203474
NM_203475
PORCN

porcupine homolog (Drosophila)

chr5_-_35974493 0.342 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr17_-_31337798 0.338 NM_032962
NM_032963
CCL14

chemokine (C-C motif) ligand 14

chr1_+_148020869 0.336 NM_000566
FCGR1A
Fc fragment of IgG, high affinity Ia, receptor (CD64)
chr1_+_202000906 0.333 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr13_-_109600709 0.330 COL4A1
collagen, type IV, alpha 1
chr5_+_149549712 0.320 NM_014228
SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr3_+_148610516 0.319 ZIC1
Zic family member 1 (odd-paired homolog, Drosophila)
chr1_-_202595666 0.318 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr13_+_113574925 0.316 NM_001143945
GAS6
growth arrest-specific 6
chr19_-_53444733 0.315 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr11_+_4859624 0.315 NM_001004759
OR51T1
olfactory receptor, family 51, subfamily T, member 1
chr12_+_26096757 0.313 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chrX_+_37777730 0.312 NM_001163334
SYTL5
synaptotagmin-like 5
chrX_+_114430547 0.311 NM_016383
LUZP4
leucine zipper protein 4
chrX_-_130250715 0.310 NM_001170963
IGSF1
immunoglobulin superfamily, member 1
chrX_-_99778340 0.303 NM_003270
TSPAN6
tetraspanin 6
chr6_-_41114905 0.301 NM_173561
UNC5CL
unc-5 homolog C (C. elegans)-like
chr1_+_158352143 0.300 NM_000702
ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chrX_+_144136798 0.297 NM_001009614
SPANXN1
SPANX family, member N1
chrX_+_102770303 0.297 NM_001006640
TCEAL1
transcription elongation factor A (SII)-like 1
chr1_+_147006065 0.295 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chrX_-_64112993 0.294 NM_001178033
NM_018684
ZC4H2

zinc finger, C4H2 domain containing

chr5_-_150501393 0.294 NM_001193544
ANXA6
annexin A6
chr1_-_120189301 0.294 NM_001047980
NBPF7
neuroblastoma breakpoint family, member 7
chr16_-_70168449 0.292 NM_000353
TAT
tyrosine aminotransferase
chr1_-_143706300 0.292 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chrX_+_148433970 0.292 NM_001171909
CXorf40A
chromosome X open reading frame 40A
chrX_+_102770547 0.291 NM_001006639
NM_004780
TCEAL1

transcription elongation factor A (SII)-like 1

chrX_-_107112244 0.290 NM_031273
TEX13B
testis expressed 13B
chrX_-_135166306 0.289 NM_001173516
MAP7D3
MAP7 domain containing 3
chrX_-_23955223 0.289 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr15_-_49184764 0.288 NM_207381
TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr1_-_143706196 0.282 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_+_148511806 0.281 NM_024579
C1orf54
chromosome 1 open reading frame 54
chr1_+_146843980 0.280 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr12_-_4358968 0.279 NM_020638
FGF23
fibroblast growth factor 23
chr13_+_51334117 0.278 NM_031290
CCDC70
coiled-coil domain containing 70
chr17_-_44249379 0.277 NM_001130918
TTLL6
tubulin tyrosine ligase-like family, member 6
chr10_+_102285690 0.273 HIF1AN
hypoxia inducible factor 1, alpha subunit inhibitor
chr15_+_22772545 0.273 SNRPN
small nuclear ribonucleoprotein polypeptide N
chrX_-_152863251 0.272 NM_002910
RENBP
renin binding protein
chrX_+_134895447 0.272 SLC9A6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr1_-_71319559 0.269 NM_005455
NM_203350
ZRANB2

zinc finger, RAN-binding domain containing 2

chr1_+_111215343 0.266 NM_001040033
CD53
CD53 molecule
chr1_-_154041393 0.266 GON4L
gon-4-like (C. elegans)
chr12_-_6668680 0.265 ZNF384
zinc finger protein 384
chr1_+_152567843 0.265 ATP8B2
ATPase, class I, type 8B, member 2
chr22_+_18388656 0.264 C22orf25
chromosome 22 open reading frame 25
chr11_+_17714070 0.264 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr17_-_33753218 0.263 NM_001004334
GPR179
G protein-coupled receptor 179
chr1_+_154386358 0.260 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr8_-_55097533 0.257 NM_006756
NM_201437
TCEA1

transcription elongation factor A (SII), 1

chrX_-_131375217 0.257 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr19_+_40824486 0.256 NM_014209
ETV2
ets variant 2
chrX_+_96025562 0.256 NM_013347
RPA4
replication protein A4, 30kDa
chr12_+_6800950 0.253 NM_014449
NM_019858
GPR162

G protein-coupled receptor 162

chr9_-_69468634 0.253 NM_001126334
FOXD4L5
forkhead box D4-like 5
chr17_-_3321782 0.253 NM_032598
NM_001170699
NM_001170698
NM_001170697
NM_001170695
NM_001170696
SPATA22





spermatogenesis associated 22





chr1_+_146827470 0.252 NM_173638
NBPF15
neuroblastoma breakpoint family, member 15
chr2_+_102136833 0.252 NM_000877
IL1R1
interleukin 1 receptor, type I
chr1_+_143326315 0.249 NM_001037675
NBPF10
NBPF9
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr1_-_120737466 0.249 NM_001004340
NM_001017986
FCGR1A
FCGR1B

Fc fragment of IgG, high affinity Ia, receptor (CD64)
Fc fragment of IgG, high affinity Ib, receptor (CD64)

chr11_-_8911110 0.248 NM_020643
C11orf16
chromosome 11 open reading frame 16
chr1_-_36338436 0.247 NM_005202
COL8A2
collagen, type VIII, alpha 2
chr1_-_120737416 0.246 FCGR1B
Fc fragment of IgG, high affinity Ib, receptor (CD64)
chr16_+_29728932 0.244 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr22_+_18388633 0.244 C22orf25
chromosome 22 open reading frame 25
chr22_+_19651446 0.243 NM_001146288
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr14_+_60045621 0.242 NM_007374
SIX6
SIX homeobox 6
chr1_-_180297372 0.242 NM_001009992
ZNF648
zinc finger protein 648
chr11_+_10480891 0.240 AMPD3
adenosine monophosphate deaminase 3
chr19_+_62434188 0.239 NM_001015879
NM_003160
NM_001015878
AURKC


aurora kinase C


chr1_-_20318578 0.239 NM_012400
PLA2G2D
phospholipase A2, group IID
chr1_-_159459814 0.237 APOA2
apolipoprotein A-II
chrX_+_149612488 0.237 NM_003828
MTMR1
myotubularin related protein 1
chr9_-_69669550 0.234 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chrX_-_153290697 0.234 NM_006730
DNASE1L1
deoxyribonuclease I-like 1
chr1_+_32703225 0.233 NM_001145720
ZBTB8B
zinc finger and BTB domain containing 8B
chr6_-_42270671 0.231 NM_002098
GUCA1B
guanylate cyclase activator 1B (retina)
chr14_-_94053933 0.229 NM_173850
SERPINA12
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12
chrX_-_137777382 0.225 NM_001139502
FGF13
fibroblast growth factor 13
chr13_+_57103789 0.225 NM_001040429
PCDH17
protocadherin 17
chr17_-_7107229 0.223 NM_001185022
CLDN7
claudin 7
chr10_-_30356344 0.223 KIAA1462
KIAA1462
chr1_-_143706265 0.222 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_120240635 0.222 NM_021794
ADAM30
ADAM metallopeptidase domain 30
chr7_+_156128431 0.221 NM_001184997
RNF32
ring finger protein 32
chr14_+_23852152 0.220 NM_181657
LTB4R
leukotriene B4 receptor
chr16_-_82633262 0.219 NM_001080442
SLC38A8
solute carrier family 38, member 8
chr1_+_174698929 0.217 NM_020318
NM_021936
PAPPA2

pappalysin 2

chr22_-_39966801 0.216 NM_138481
CHADL
chondroadherin-like
chr12_+_48784057 0.216 NM_005276
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chrX_+_102498035 0.216 NM_001006612
NM_001006613
NM_001006614
NM_016303
WBP5



WW domain binding protein 5



chr11_-_117600918 0.215 NM_001098526
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr3_+_11009419 0.214 NM_003042
SLC6A1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr16_+_68516401 0.213 NM_199424
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr22_-_35835548 0.211 TMPRSS6
transmembrane protease, serine 6
chr14_-_93914634 0.210 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr9_+_42707229 0.210 NM_001099279
NM_199244
FOXD4L2
FOXD4L4
forkhead box D4-like 2
forkhead box D4-like 4
chr3_-_135131207 0.210 NM_025041
C3orf36
chromosome 3 open reading frame 36
chr10_+_50487146 0.207 NM_020984
CHAT
choline O-acetyltransferase
chrX_-_138742050 0.206 NM_001010986
NM_173694
ATP11C

ATPase, class VI, type 11C

chrX_-_151037066 0.203 NM_021049
MAGEA5
melanoma antigen family A, 5
chr11_+_72660894 0.203 NM_004154
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_+_116717404 0.203 ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr3_-_122862447 0.202 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr9_-_14769530 0.201 NM_001177704
FREM1
FRAS1 related extracellular matrix 1
chr3_+_63403792 0.198 NM_144642
SYNPR
synaptoporin
chr14_-_63079299 0.198 PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr1_-_155336223 0.197 NM_001004341
ETV3L
ets variant 3-like
chr1_-_151679126 0.197 NM_001045479
S100A7L2
S100 calcium binding protein A7-like 2
chr1_-_150805852 0.196 NM_178435
LCE3E
late cornified envelope 3E
chr1_-_109853808 0.196 NM_020703
AMIGO1
adhesion molecule with Ig-like domain 1
chr15_-_41728329 0.195 NM_054020
NM_172095
NM_172097
CATSPER2


cation channel, sperm associated 2


chr11_+_75106512 0.195 NM_025098
MOGAT2
monoacylglycerol O-acyltransferase 2
chr20_+_19863716 0.193 RIN2
Ras and Rab interactor 2
chr12_-_118725672 0.192 CIT
citron (rho-interacting, serine/threonine kinase 21)
chr15_-_60244773 0.192 NM_001007595
C2CD4B
C2 calcium-dependent domain containing 4B
chr22_-_49363711 0.192 NM_004377
NM_152246
NM_001145134
NM_001145135
NM_001145136
NM_152245
CPT1B





carnitine palmitoyltransferase 1B (muscle)





chrX_-_52403720 0.191 NM_130777
XAGE2
X antigen family, member 2
chr1_-_23683214 0.190 ASAP3
ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr8_-_22841173 0.187 NM_144962
PEBP4
phosphatidylethanolamine-binding protein 4
chr11_-_27677755 0.187 NM_170734
BDNF
brain-derived neurotrophic factor
chr9_+_137107007 0.187 OLFM1
olfactomedin 1
chr19_-_53187151 0.187 NM_001128326
BSPH1
binder of sperm protein homolog 1
chrX_+_99786044 0.185 SRPX2
sushi-repeat containing protein, X-linked 2
chr1_-_201420927 0.184 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr19_-_7598204 0.184 XAB2
XPA binding protein 2
chr1_+_20385164 0.184 NM_152376
UBXN10
UBX domain protein 10
chr19_-_63550712 0.183 A1BG
alpha-1-B glycoprotein
chr11_-_125055884 0.182 NM_001612
NM_020069
NM_020107
NM_020108
NM_020109
NM_020110
NM_020111
NM_020113
NM_020115
ACRV1








acrosomal vesicle protein 1








chr21_+_44549486 0.182 PFKL
phosphofructokinase, liver
chr4_-_154900599 0.182 RNF175
ring finger protein 175
chr11_-_1974636 0.181 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr17_-_38421363 0.181 VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr12_-_6668787 0.181 NM_001039918
NM_133476
ZNF384

zinc finger protein 384


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.